IROCAP–LP

(Liposomal Ferric Di-Phosphate + Vitamin C + Folic Acid + Vitamin B12)

Advanced Renal Anemia Correction Therapy

PRODUCT INTRODUCTION

Brand Name: IROCAP–LP
Composition:

• Liposomal Ferric Di-Phosphate
• Vitamin C
• Folic Acid
• Vitamin B12

Category: Oral Iron – Advanced Liposomal Technology

 

 CLINICAL BACKGROUND

In CKD & Dialysis Patients:

• Iron deficiency common
• Reduced erythropoiesis
• ESA therapy requires iron support
• Poor absorption of conventional iron
• GI intolerance reduces compliance

👉 Liposomal iron improves absorption and tolerability.

 MODE OF ACTION (MOA)

🔹 Liposomal Ferric Di-Phosphate

• Encapsulated in phospholipid membrane
• Protects iron from gastric degradation
• Absorbed via lymphatic pathway
• Bypasses hepcidin-mediated blockade

🔹 Vitamin C

• Enhances iron absorption
• Converts ferric to ferrous form

🔹 Folic Acid & Vitamin B12

• Support DNA synthesis
• Essential for RBC maturation

Overall Clinical Effect:

✔ Improves Hb levels
✔ Reduces GI irritation
✔ Enhances response to ESA
✔ Better compliance

INDICATIONS

• Iron deficiency anemia
• CKD-associated anemia
• Dialysis patients
• Pregnancy-related anemia (as advised)
• Patients intolerant to conventional iron

 DOSAGE

As prescribed by physician
Usually once daily

 FEATURE – ADVANTAGE – BENEFIT (FAB)

🔹 Feature

Liposomal iron with hematinic vitamins

🔹 Advantage

Better absorption with minimal GI side effects

🔹 Benefit

Higher compliance & faster Hb correction

USP

✔ Liposomal technology
✔ Reduced constipation
✔ Better bioavailability
✔ Ideal adjunct to ESA therapy
✔ Renal-segment positioning

 

SAFETY PROFILE

• Mild GI discomfort possible
• Dark stools (normal finding)
• Generally well tolerated
• No major constipation compared to traditional iron