NIFIGARD XL-30/60

(Nifedipine Sustained Release Tablets IP 30/60 mg)

Brand: NIFIGARD XL-30/60

Generic Name: Nifedipine

Category: Calcium Channel Blocker (CCB) – Sustained Release

 

Sustained Blood Pressure Control with Long-Lasting Protection

 

PRODUCT INTRODUCTION

Brand Name: NIFIGARD XL-30/ 60

Generic Name: Nifedipine Sustained Release

Strength:

• 30 mg and 60 mg

Pharmacological Class:

Dihydropyridine Calcium Channel Blocker

NIFIGARD XL-30/60 is designed for long-acting blood pressure control and cardiovascular protection.

The sustained-release formulation provides:

• Smooth BP control
• 24-hour therapeutic coverage
• Reduced BP fluctuations

 

CLINICAL BACKGROUND 

Hypertension is a major risk factor for:

• Heart attack
• Stroke
• Kidney disease
• Heart failure

Uncontrolled blood pressure causes:

• Increased vascular resistance
• Arterial stiffness
• Damage to heart and kidneys

Calcium channel blockers like Nifedipine help relax blood vessels and reduce blood pressure.Sustained-release formulations provide stable blood levels and better compliance.

MODE OF ACTION (MOA)

Nifedipine works by blocking L-type calcium channels in vascular smooth muscle.

Mechanism

• Prevents calcium entry into vascular smooth muscle cells.
• Causes vasodilation of arteries.
• Reduces peripheral vascular resistance.

Result

Lower blood pressure

Improved blood flow

Reduced cardiac workload

INDICATIONS

NIFIGARD XL-30/ 60 is used in:

• Hypertension
• Angina pectoris
• Coronary artery disease
• Vasospastic angina
• Raynaud’s phenomenon (sometimes used)

DOSAGE

Typical dosage:

1 tablet once daily

(or as prescribed by physician)

Because of sustained release, it provides extended BP control throughout the day.

FEATURE – ADVANTAGE – BENEFIT (FAB)

Feature–Sustained-release Nifedipine formulation.

AdvantageProvides gradual drug release for long-lasting effect.

Benefit— Maintains stable blood pressure with better patient compliance.

USP (UNIQUE SELLING PROPOSITION)

Sustained-release formulation

Long-acting BP control

Improves vascular relaxation

Reduces cardiovascular risk

Once-daily dosing improves compliance

Positioning: Long-acting calcium channel blocker for stable BP control.

SAFETY PROFILE

Generally well tolerated.

Possible side effects:

• Headache
• Flushing
• Dizziness
• Pedal edema

Usually mild and dose-dependent.