STAFOCET-M

(Levocetirizine + Montelukast Tablet / Syrup)

Dual Anti-Allergic & Anti-Inflammatory Therapy

 PRODUCT INTRODUCTION

Brand Name: STAFOCET-M
Category: Anti-allergic Combination

Composition:

• Levocetirizine
• Montelukast

Available As:

• Tablet
• Syrup (Pediatric-friendly)

 

 CLINICAL BACKGROUND

Allergic conditions are very common:

• Allergic rhinitis
• Seasonal allergy
• Dust allergy
• Chronic urticaria
• Pediatric recurrent cold
• Asthma with allergic component

Pathophysiology involves:

✔ Histamine release
✔ Leukotriene-mediated inflammation

👉 Dual blockade improves symptom control.

 MODE OF ACTION (MOA)

🔹 Levocetirizine

• H1 receptor antagonist
• Blocks histamine action
• Reduces sneezing, itching, rhinorrhea

🔹 Montelukast

• Leukotriene receptor antagonist
• Reduces airway inflammation
• Decreases bronchoconstriction
• Controls allergic rhinitis & asthma component

Combined Effect:

✔ Reduces allergy symptoms
✔ Controls inflammation
✔ Prevents recurrence

 INDICATIONS

• Allergic rhinitis
• Seasonal allergies
• Chronic urticaria
• Pediatric allergic cough
• Asthma with allergic component
• Recurrent allergic cold

 

 DOSAGE

• Once daily (usually evening)
• Syrup dose based on age/weight
• As prescribed by physician

 FEATURE – ADVANTAGE – BENEFIT (FAB)

🔹 Feature

Dual anti-allergic mechanism

🔹 Advantage

Blocks histamine + leukotriene pathways

🔹 Benefit

Better symptom control & reduced recurrence

USP

✔ Dual pathway control
✔ Once-daily dosing
✔ Available in tablet & syrup
✔ Effective in pediatric& adult patients
✔ Controls night-time allergy symptoms

 

SAFETY PROFILE

• Mild drowsiness (Levocetirizine)
• Generally well tolerated
• Rare behavioral changes (monitor in pediatric use)
• Safe under prescription