ASTADOL-P

(Aceclofenac + Paracetamol)

🟢 ASTADOL-SP

(Aceclofenac + Paracetamol + Serratiopeptidase)

Powerful Pain Relief with Anti-Inflammatory Action

 PRODUCT INTRODUCTION

🔹 ASTADOL-P

Composition:

• Aceclofenac-100 MG
• Paracetamol-325 MG

Category: Analgesic + Anti-inflammatory

🔹 ASTADOL-SP

Composition:

• Aceclofenac-100 MG
• Paracetamol-325 MG
• Serratiopeptidase-15 MG

Category: Analgesic + Anti-inflammatory + Anti-edema enzyme

 CLINICAL BACKGROUND

Pain involves:

✔ Prostaglandin-mediated inflammation
✔ Tissue injury
✔Edema formation

Aceclofenac reduces inflammation.
Paracetamol reduces pain & fever.
Serratiopeptidase reduces swelling &edema.

MODE OF ACTION (MOA)

🔹Aceclofenac

• NSAID
• Inhibits COX enzymes
• Reduces prostaglandin synthesis
• Decreases inflammation & pain

🔹 Paracetamol

• Central analgesic
• Antipyretic
• Enhances pain control

🔹Serratiopeptidase (ASTADOL-SP)

• Proteolytic enzyme
• Breaks inflammatory proteins
• Reduces edema& swelling

Combined Effect:

✔ Pain relief
✔ Reduced inflammation
✔ Faster recovery
✔ Better mobility

 INDICATIONS

• Osteoarthritis
• Rheumatoid arthritis
• Back pain
• Cervical spondylosis
• Dental pain
• Post-operative pain
• Trauma
• Swelling & soft tissue injury (SP preferred)

 DOSAGE

• Usually twice daily after food
• As prescribed by physician

 FEATURE – ADVANTAGE – BENEFIT (FAB)

🔹 ASTADOL-P

Feature: Aceclofenac + Paracetamol
Advantage: Dual pain pathway control
Benefit: Stronger & faster pain relief

🔹 ASTADOL-SP

Feature: Triple combination
Advantage: Anti-inflammatory + anti-edema
Benefit: Faster swelling reduction & recovery

USP

✔ Balanced analgesic therapy
✔ Strong anti-inflammatory action
✔ SP variant for post-surgical swelling
✔ Good GI tolerability (compared to diclofenac)
✔ Widely accepted molecule

 

 

SAFETY PROFILE

• Use after meals
• Avoid in severe gastric ulcer
• Caution in renal impairment
• Avoid prolonged uncontrolled use
• Generally well tolerated under supervision

RENPURE